Changing the Dynamics in Healthcare Research with Ansys Software

Scientific breakthroughs in healthcare are increasing daily. However, the costs of new drugs and devices are prohibitive and making them available can take years before they are approved by authorities such as the FDA. Traditionally, to gain approval for a new healthcare drug or device, it had to undergo comprehensive testing in three disciplines; bench tests (in vitro), animal tests (in vivo) and finally, clinical trials (in situ). This process can take a decade before a new drug or device is regarded as effective and safe enough to be brought to market. What is more, a large number of new products fail 90% of the way through the journey.

The development of scientific software applications that can assist in and accelerate the process is bringing a new dynamic, helping to bring down costs while reducing the risk of failure of a drug or device. Simulation software provides a new means of testing any prototype healthcare device, and is becoming increasingly important in biomechanical research and is commonly referred to as in silico testing, referring to the silicon chips that are integral to any computer. Software vendors such as Ansys have collaborated in integrating their software in healthcare modelling and simulation, assisting in breakthroughs in healthcare device development.

Accommodating the New Market

Traditionally, software such as Ansys was developed for the engineering industry and is known as computer-assisted engineering (CAE). While CAE software that can perform functions such as finite element analysis (FEA) and computational flow dynamics (CFD) is what is needed for in silico testing, healthcare researchers are generally untrained in these disciplines, especially in the pharmaceutical industry. Ansys themselves speak of the need to “democratize” their software tools, making them accessible to all, not just the few researchers with the necessary training in mathematics and engineering. They have already made inroads on providing a product that can be used by anyone in healthcare. Surgeons can use simulation before an operation to assess the effect of a particular approach on a patient. Sales and marketing can demonstrate how a product functions via simulations. Even executives can use a simulation model to secure funding from potential investors.

Ansys has collated a portfolio of case studies where the use of their products has brought benefits to healthcare organizations, primarily via reduced costs and shorter timeframes as well as risk reduction. The ability to show a simulation as opposed to describing it has an impact all along the value chain:-

  • investors can visualize what the innovation does
  • regulatory authorities get a clear view of how the product works
  • potential customers, such as doctors and hospitals, are likely to adopt the new product from a demonstration
  • insurers are presented with visual evidence to help them make a decision about a patient procedure and how likely it is to succeed.

From Cardiac Interventions to Better Pills

  • Heart Disease. The medical world is focused on combatting cardiovascular disease, because it is the leading cause of death globally, according to the WHO. The traditional procedure of open-heart surgery is steadily being replaced by less invasive remedies, such as inserting a stent to regulate blood flow. CFD is invaluable in this field, from making more accurate diagnosis of the state of a patient’s arteries to manufacturing new stents that work more effectively than current models.
  • Pulmonary Applications. New drugs can cost as much as $1-billion to develop, and those for respiratory diseases are the most expensive, because of the difficulty of testing the drug’s effectiveness in the field. Researchers are turning to CFD to simulate the movement of air through the respiratory passages. In silico simulation can reduce the cost of development by as much as 30% and halve the time to complete the testing.
  • Dietary Supplements. It goes without saying that if a pill is too large and difficult to swallow, it will not be marketable. The ideal shape is as round as possible, but this affects the hardness of the pill, which in turn compromises the machinery punching out the pill and reduces the lifetime of the parts. Asahi in Japan have expanded their product range from brewing beer to providing dietary supplements. They used Ansys Mechanical to come up with a solution that saved them hundreds of thousands of dollars.

There are many more examples of the use of simulation in healthcare available on the Ansys website, but these few give an idea of the diversity of applications that can benefit from CAE.

So How Does this Affect the License Administrator?

Up to now, CAE software has been used by specialists and experts, even in engineering, so there are usually only a few simulation software applications on site. Now that Ansys is “democratizing” its product and making it accessible to people who are not skilled in modelling and simulation, the need for the product across the organization will increase, and so will the number of licenses required. Ansys provides FlexLM as a license manager, as do most of their competitors, notably Comsol and Dassault. While FlexLM reports salient information on license usage, it is for the benefit of the vendor, rather than the customer.

This is where OpenLM can play an important role, as it can provide all the control and visibility required to manage other licenses, such as MatLab, as well as Ansys, through a single graphical interface (GUI). What is more, OpenLM’s core product can manage licenses for Nvidia GPUs (graphical processing units), which are being used by more and more organizations running simulation software, because of the reduction in time taken to process the information. Ansys has cooperated with Nvidia to make their software very scalable, for instance, for performing simulations, Ansys Mechanical can scale up to 1 000 cores as opposed to the industry standard of 100 cores, and can solve up to 2 billion DOF (degrees of freedom). Ansys’ CFD tool, Fluent, can scale up to 129 000 cores.

OpenLM can also manage the Ansys “pay-as-you-go” licensing model, the “Elastic License”. This license can be used as a supplement to the regular Ansys agreement. It allows the customer to “top-up” where required, for instance, where there is a peak demand for a new project. It is a much more customer-friendly license model, in that it has reporting that supports departmental and project chargebacks.

Where Ansys is leading currently, its competitors will surely follow suit. In a few years time, it is likely that specialized and rare CAE software will no longer be used by only a handful of finite element specialists, but by resources across the organization. Managing software such as the Ansys Workbench is just as easy as managing Autodesk products with OpenLM, as well as the GPUs required for the necessary processing power. One of our consultants can advise you on your unique situation.

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The Engineering Software Alphabet Soup

 

Engineering software has grown in leaps and bounds since the first engineering products were developed. Where initially the focus was on computer-aided design, or CAD, now it has extended to provide digitized support to all areas of engineering. There are thousands of engineering software tools available today, many of which fall into categories that have a three-letter acronym to describe them. Managing compliance of all these products with vendor agreements has become an important discipline for the IT business unit, and the license management team in many engineering companies have come to rely on OpenLM in helping them manage the “alphabet soup”. We have compiled a list of some of these acronyms, and the products supported by OpenLM that fall under these categories.

BIM – Building Information Modelling

Building Information Modelling software has evolved from the original concept of 2D and 3D CAD. BIM provides the architect and engineer with 3D models of proposed and existing built structures. It can be used both for individual buildings and for whole ecosystems, like smart cities. The power of BIM is its ability to identify potential construction errors and weaknesses. Some of the BIM tools that OpenLM supports are Autodesk’s Revit and Navisworks, Tekla BIMSight, Dassault Systemes BIM, and BricsCAD BIM.

CAD – Computer-aided design

Computer-aided design heralded the revolution in engineering life, providing a software alternative to the drawing board and pens. Now available for 3D as well as 2D drawing, every engineering and architectural company has at least one CAD tool in their portfolio. While OpenLM is known for its ability to manage licenses for AutoDesk’s AutoCAD, it also supports BricsCAD, PTC Creo, Dassault’s Catia and Ansys, among many others.

CAE – Computer Aided Engineering

Computer-aided engineering performs analytics and simulations on engineering designs, such as computational flow dynamics (CFD), finite element analysis (FEA) and multibody dynamics (MDB) among other disciplines. Typically, such software is composed of a pre-processor, solver and a post-processor, and receives the output of design executed using a CAD or similar design application.

MSC Software were one of the earliest companies offering software for various types of CAE, such as Adams Car. Other CAE software includes Mathworks Simulink, Matlab, and Wolfram’s Mathematica, all of which are in OpenLM’s vendor list.

CAM – Computer-Aided Manufacturing

Computer-aided manufacturing usually describes an automated manufacturing process and is not engineering software per se, but does receive output from CAD and CAE application as part of the value chain and often requires the supervision or intervention of experienced engineers. Many vendors of engineering software offer CAM solutions, including Dassault (Catia), Siemens (NX CAM), PTC (Creo), AutoDesk (Powermill, FeatureCAM and Fusion 360) and HCL Technologies (Camworks). All of these vendor products are supported by OpenLM..

CFD – Computational Flow Dynamics

Computational Flow Dynamics or CFD is used to analyse the flows of gases and liquids via simulation and is one of the CAE analytic tools. Typically, like most CAE tools, CFD analysis is very complex and is run using multiple CPUs and/or GPUs.

Many major vendors offer CFD software, notably Ansys, which has products such as Fluent, CFD and CFX. Other well-known products include Autodesk’s Inventor and CFD, MSC’s Dytran and Solidworks.

ECAD – Electronic Computer Aided Design

Electronic Computer-Aided Design (ECAD) is a special branch of software that is dedicated to the design and production of Printed Circuit Boards (PCBs). The “CAD” in the name is a bit misleading, CAD is focused on design, while the best ECAD products cover the whole board manufacture process from design through to assembly and even parts explosion and bill of materials (BOM) generation.

One of the leaders in this field is Cadence Software with its Allegro software, which is focused on the design aspect, and some other products that are devoted to MCAD, the manufacture aspect, and IDX that allows electronic and mechanical engineers to collaborate on the board design and manufacture. OpenLM also supports Mentor Graphics’Xpedition PCB engineering suite.

EDA – Engineering Design Automation

Another acronym that is synonymous with EDT.

EDT – Engineering Design Tools

EDT is a global term for specialized engineering software, and includes any software that the engineer could find in his digital “toolbox”.

FEA and FEM – Finite Element Analysis and Method

Finite element analysis (FEA) is one of the CAE family of software. FEA software performs simulations and is usually run in batch mode. There is a wide variety of FEA software available, such as Simulia’s Abaqus, Nastran, originally from NASA and now available from MSC and Siemens, Livermore’s LS-DYNA and Ansys. There are many FEA packages that originated in universities and through research. These generally do not come with a license manager, but OpenLM has a feature that allows software like this to be monitored.

GIS – Geographical Information System

Geographic information systems (GIS) have been around for a long time and ArcGIS was the software that OpenLM is founded on. The founders were working at a company that used the ESRI product extensively, and the need for an independent license manager was identified. They started up a company that initially offered a solution for ArcGIS license management, then AutoCAD, followed by software from many other vendors. Today over 900 customers rely on OpenLM to manage their licenses, in industries ranging from Aerospace to scientific research.  

GPU – Graphics Processing Unit

What was originally a circuit board designed to support computer games has become a vital cog in modern computing. The parallel processing capabilities of graphics cards cuts down processing time and costs on intensive software processing required by CAE applications. Nvidia is the leading producer in the GPU field and they have collaborated with some of the leading software vendors, such as Dassault to optimise processing using the Nvidia boards. Recently OpenLM was requested to include Nvidia license management as part of the supported vendor products and this has been done. This simplifies work in advanced simulations and calculations, where cost of processing is an important consideration.

MDB – Multibody Dynamics

Multibody dynamics (MDB) is a CAE software tool. The discipline examines the behaviour of mechanical moving parts and the influences of external forces on these parts. Because the effects of these forces are unpredictable and cause friction and instability, this software can predict weaknesses and other potential flaws as well as mean time to failure. Some major software vendors in this field are Comsol, who have a Multibody Dynamics Module, and MSC Software with its Adams, Adams Car and SimXpert products.

PLM – Product Lifecycle Management

Early engineering software was siloed into different areas of expertise, and did not integrate readily with other applications used in the overall production of a part or product. This has been changed with the introduction of product lifecycle management (PLM) which covers the whole value chain of product development from inception to market. It also goes beyond this in that it supports maintenance during the product’s life up to the time when it needs to be disposed of as it has reached the end of its life. Some of the Enterprise Resource Planning (ERP) software also lays claim to PLM management, but the main players in the PLM space are, Siemens, Dassault and Autodesk.

The Wide World of Engineering Software

These are not the only acronyms in the alphabet soup, and there are also many products that do not have a handy acronym to classify them that are used in various industries and engineering disciplines. Building roads and bridges, communicating via radio and satellite, designing transmission networks and the many facets of the oil and gas industry, all have their own specialized software tools. OpenLM covers many of these products too. If you are looking for effective license management over your valuable software, why not try our product and see if it works for you. You can download an evaluation copy and try it for 30 days at https://www.openlm.com/download/.

 

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OpenLM Software University Program

OpenLM is a worldwide operating software specialist for management and monitoring of network licenses (floating, concurrent user, token based) utilization. OpenLM’s Software provides a comprehensive management solution for license management software such as FLEXlm, FLEXnet, Sentinel RMS, Sentinel HASP, RLM, IBM LUM DSLS and LM-X.

Universities naturally hold an extensive profile of licensed software applications, a vast population of users set in various groups, and different levels of license usage permissions. Handling a database of this magnitude and complexity is a real challenge.

This is where OpenLM’s benefits show. OpenLM eases the management of diverse license databases, and introduces the option for cost allocation per usage for software licenses, thus reducing usage costs considerably, and minimizing the need for further license acquisition.

In order to improve OpenLM’s cooperation with universities, OpenLM has introduced its new university program. This program provides a professional solution for universities to manage and monitor the utilization of software products like CAD, CAE, Software Engineering and GIS. The program’s pricing scheme takes the universities’ financial considerations into account.

We are convinced that the apparent assets that the OpenLM software brings to license management would be highly appreciated by Universities, and that these benefits would be embraced by faculties such as Engineering (Electrical, Mechanical, Aerodynamics, etc), Physics, Informatics, Architecture and Geo-sciences. OpenLM has been known to improve the utilization of prominent licensed application such as  Autodesk Autocad, ESRI ArcGIS, MATLAB, PTC and CATIA by as much as 30%.

Universities and departments that are interested in this program should contact OpenLM through info@openlm.com.

 

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